Epidemiology and Informatics
Public Health

What would you like to do?

What you need to know

​​​​​​Electronic Submission of Immunization Records

The electronic reporting of immunization data is a public health core objective for eligible hospitals, critical access hospitals (CAH), and eligible professionals attesting to Stage 3 Meaningful Use (MU).

The Nebraska State Immunization Information System (NESIIS) is an immunization system designed to consolidate patient immunization records into one complete, accurate and definitive immunization record.​

NESIIS is able to do the following:

  • Uni-directional Data Exchange
  • Bi-directional Data Exchange

What is bi-directional exchange? In order to be bi-directional with NESIIS, you must be able to query patient records in NESIIS from within your EHR interface. An example of this would be pulling up a record in your EHR, then clicking a button to query NESIIS for that same person's record to see if additional information can be found.

For more information regarding bi-directional data exchange with NESIIS please contact our Help Desk at 402-471-0133, toll-free line 888-433-2510, or

Information on bi-directional support is found within our HL7 specifications.

  •  Accept and send HL7 2.3.1 formatted data
  •  Accept and send HL7 2.5.1 formatted data
  •  Accept and send data electronically via PHINMS and SOAP Web Services