Epidemiology and Informatics
Public Health

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What you need to know

​​​​The Nebraska State Immunization Information System (NESIIS) is a secure, statewide, web-based system that connects and shares immunization information among public clinics, private provider offices, local health departments, schools, hospitals, and other health care facilities that administer immunizations and provide medical care to Nebraska residents.

NESIIS maintains computerized immunization data for people of all ages in a confidential and secure manner.

NESIIS helps to service the public health goal of preventing the spread of vaccine preventable diseases. A major barrier to reaching this goal is continuing difficulty of keeping immunization records accurate and up-to-date. It's difficult for providers and parents to accurately assess the immunization status of their children and patients when records are scattered between medical provider offices and parent records. NESIIS can help eliminate missed opportunities and over- immunization by providing one secure location to store complete immunization records. 

​NESIIS helps ensure that children get only the vaccines they need, and at the same time, improves the efficiency of the office (private, public, state) by reducing the time needed to find, assess, and document a patient's immunization status.



NESIIS Contact Information
Department of Health & Human Services
Phone Number
(402) 471-0133
Toll Free Number
(888) 433-2510