Antimicrobial Resistance

Epidemiology and Informatics
Public Health

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What you need to know

​​​​​What is Antimicrobial Resistance?

Antimicrobial resistance results when bacteria or other microorganisms become able to resist the killing activity of antimicrobials. Microorganisms become resistant due to excess use of antimicrobials. Use antimicrobials only for conditions where there is evidence that antibiotics are effective. Avoid them for conditions where they do not help, such as the common cold.

What is Multi-Drug Antimicrobial Resistance?

Multi-drug resistant organisms or MDROs are bacteria that can resist several kinds of antibiotics. MDROs are harder to treat. Examples of MDROs include:

  • MRSA (methicillin-resistant Staphylococcus aureus)
  • Vancomycin-resistant Enterococcus (VRE)
  • Vancomycin intermediate or resistant S. aureus (VISA or VRSA)
  • Carbapenem-resistant enterobacteriaceae (CRE)
  • CRPA (Carbapenem Resistant Pseudomonas aeruginosa and CRAB (Carbapenem Resistant Acinetobacter baumanii)
  • Candida auris.

What is the Nebraska HAI Program Doing to Decrease Antimicrobial Resistance?

What Can I Do to Reduce Resistance to Antimicrobials?

  • Wash your hands. Hand washing is the simplest but most effective way of reducing spread of resistant bacteria.
  • Ask your prescriber if you need antibiotics. Do not insist on antibiotics if he or she does not recommend them.
  • Take antibiotics for as long as your prescriber said. Do not stop without notifying your prescriber. This way, any leftover resistant bacteria will not have a chance to develop.

Antibiogram: Statewide and Regional (Gram Negative Bacteria)

expand Year : 2021 ‎(19)
​​Additional Information

Antibiotic stewardship is the overall effort and programs that promote appropriate and correct antibiotic prescribing. 

Why Antibiotic Stewardship?

  • Antibiotic resistance is a real and increasing problem.
  • 30-50% of antibiotic use in hospitals is unnecessary or inappropriate.
  • Excess use of antibiotics also adds to the growing problem of Clostridium difficile infections.

Advantages of reducing the use of antibiotics when there is no need for them:

  • Decrease resistance to antibiotics.
  • Fewer Clostridium difficile infections.
  • Reduction in healthcare costs.
  • Better patient outcomes

Efforts in Nebraska to Promote Antibiotic Stewardship

  • Nebraska Antimicrobial Stewardship and Assessment Program (ASAP)  is a program at Nebraska Medicine. The program has the support of Nebraska DHHS. ASAP provides guidance to facilities that develop programs for antibiotic stewardship. ASAP develops tools to help build stewardship programs.
  • MDStewardship  is a group of doctors specializing in infectious disease. These Omaha-based doctors provide telestewardship to remote facilities. Their services may be available to some critical access hospitals in rural areas through scholarships. Hospitals can also consult with the doctors privately.
  • Great Plains Quality Innovation Network (GPQIN)  promotes antimicrobial stewardship through two programs. One is in outpatient settings and the other is` in long-term care facilities.

Stewardship Resources from CDC